Harold E. Van Wart, Ph.D.

Dr. Van Wart has served as CymaBay Therapeutic’s Chief Executive Officer and a member of the Board of Directors since January 2003, and President since April 2001. He served as Chief Operating Officer from December 2002 to January 2003 and Senior Vice President, Research and Development from October 2000 to December 2002. From 1999 to 2000, Dr. Van Wart was Vice President and Therapy Head for arthritis and fibrotic diseases at Roche Bioscience, a biopharmaceutical company. From 1992 to 1999, he was Vice President and Director of the institute of biochemistry and cell biology at Syntex Corporation, a biopharmaceutical company acquired by Roche Bioscience in 1994. From 1978 to 1992, Dr. Van Wart served on the faculty of Florida State University. He currently serves on the Emerging Companies and Health Section Governing Boards of the Biotechnology Industry Organization (BIO), as well as on its board of directors. He is also a Director of Conatus Pharmaceuticals, Inc. and the California Life Sciences. Dr. Van Wart holds a Ph.D.