How to Simplify ADC Characterization
Virtual Event
Characterizing a lysine-conjugated ADC with 3-4 drug molecules scattered across dozens of possible sites is a daunting analytical challenge — but with the right enzymatic strategy and analytical workflows, it becomes straightforward. Arginine-specific digestion with GingisREX eliminates the missed cleavages that plague trypsin-based peptide mapping of conjugated lysines, producing cleaner chromatograms and more reliable quantification...
