Biodistribution, Target Engagement and PK/PD for Antibody/ADC/Nucleotide/Novel Protein-Based Therapeutics: Quantitative Assessment and Translation
Predicting pharmacokinetics (PK), pharmacodynamics (PD), and target engagement in tissues that cannot be sampled clinically is a major challenge in drug development. This workshop will present current modeling and experimental strategies to assess the biodistribution of large molecule therapeutics, such as antibodies, peptides, and nucleic acid-based medicines. A key focus will be on translating these..