The investigational new drug application (IND) application is an important step in a drug development program, and understanding the requirements for a successful IND filing is utmost important to ensure fast and efficient development. While the principles and basics are similar across different modalities for an IND filing such as safety studies, there are important..
Investigational new drug (IND) application is an important milestone that marks the entry of a molecule into clinical development. Knowing the objectives, expectations, and processes of assembling and filing an IND is the key to not only a successful filing but also a promising clinical development path forward. Often, there are cases where too many..
From Lead Optimization and Candidate Nomination Through Clinical Development It is well known that a majority of small molecule late discovery and development pipelines are populated by compounds that are poorly soluble, and/or permeable. This has resulted in increasing use of established and emerging technologies to address these limitations. There are multiple ways that enabling..